Renal Vascular Disease & Systemic Diseases with Renal Manifestations

By completing this question set, you will be able to distinguish atherosclerotic renal artery stenosis from fibromuscular dysplasia and explain why ACE inhibitors are dangerous in bilateral RAS. You will differentiate the three thrombotic microangiopathies (TTP, typical HUS, atypical HUS) by their dominant organ involvement, age, triggers, and treatments. You will distinguish benign from malignant nephrosclerosis by histopathology and identify scleroderma renal crisis as the condition where ACE inhibitors are the treatment of choice. You will recognize the renal effects of preeclampsia and hepatorenal syndrome as hemodynamic/functional injuries in specific clinical contexts. You will identify the renal manifestations of multiple myeloma, sickle cell disease, and tumor lysis syndrome, and explain the specific mechanism by which each hematologic/oncologic disease injures the kidney.