Foundational Microbiology · Molecular targets, mechanisms of action, resistance patterns, and mechanism-based toxicities of all major antimicrobial drug classes
By completing this question set, you will map every major antimicrobial drug class to its molecular target and explain why that target is selectively exploitable — the bacterial PBP cross-linking that beta-lactams block is absent in human cells; the 70S ribosomal subunits of bacteria differ structurally from human 80S ribosomes; viral thymidine kinase activates acyclovir selectively in infected cells; fungal ergosterol differs from human cholesterol; Plasmodium heme polymerization has no human analog.